Renard-Nozaki J., Kim T., Imakura Y., Kihara M. and Kobayashi S. 1989. Effect of alkaloids isolated from Amaryllidaceae on herpes simplex virus. Research in Virology, 140: 115-128.
Gabrielsen B., Monath T.P., Huggins J.W., & al. 1992. Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances. J. Nat. Prod., 55: 1569-1581.
Husson G.P., Sarrette B., Vilagines Ph., Vilagines R. 1993. Investigations on antiviral action of Haemanthus albiflos natural extract. Phytotherapy Research, vol.7, p. 348-351.
Husson G.P., Lai-Kuen R., Vilagines R. 1997. Effet antiviral d'Haemanthus albiflos sur le système: virus de Moloney, cellule épithéliale de souris. (Système modèle pour l'étude d'un effet éventuel sur le H.I.V.) Compt. Rd. Soc. Biol. de France. T. 191, N° 3, p. 473-485.
Szlávik L., Gyuris Á., Minárovits J., Forgo P., Molnár J., Hohmann J. 2004. Alkaloids from Leucojum vernum and antiretroviral activity of Amaryllidaceae alkaloids. Planta Med., 70: 871-873.
Antibactérien
Action sur la transformation bactérienne
Miriuta AIu, Pererva TP, Mozhilevskia LP, Kunakh VA. 2005. [Article in Russian] [The influence of the extract of Ungernia victoris cultured cells and of some metal cations on Escherichia coli transformation with plasmid DNA]. Tsitol Genet. 39(6):24-9.
Myryuta A.Yu., Pererva T.P. 2008. Biological activity of Ungernia victoris extract in the Escherichia coli CaCl2-transformation system in the presence of calcium channel modulators. Cytology and Genetics, 42(4): 45-49.
Antifongique
Sur, A.D., E. Gurkan, et al. 1999. The antifungal activity of Pancratium maritimum. Fitoterapia. 70(2): 187-189.
Four known alkaloids, lycorine (1), 1-2-di-O-acetyl-lycorine(2), ambelline(3), and crinine(4) were isolated from the bulbs of Brunsvigia littoralis. 1H-and 13C-NMR spectra of 2 were completely assigned by means of 1D-2D-NMR techniques. The alkaloids (1-4) together with the synthesised 11-O-acetylambelline (3a) and 3-O-acetylcrinine (4a)were tested for antimalarial activity with two strains of cultured (Plasmodium falciparum) and for cytotoxicity with BL6 mouse melanoma cells. Alkaloids 1 and 2 exhibited both antimalarial and cytotoxic activity.
Ali H, Konig GM, Khalid SA, Wright AD, Kaminsky R. 2002. Evaluation of selected Sudanese medicinal plants for their in vitro activity against hemoflagellates, selected bacteria, HIV-1-RT and tyrosine kinase. inhibitory, and for cytotoxicity. J. Ethnopharmacol. 83(3): 219-228.
[abstract]
"Pamianthe peruviana (Amaryllidaceae) exhibited significant
activity against a chloroquine-resistant Plasmodium falciparum strain (K1) and a
chloroquine-sensitive strain (NF54) with IC(50) values of 0.6 and 1.1 &mgr;g/ml,
respectively. Additionally, P. peruviana showed considerable activities against
Trypanosoma brucei rhodesiense (IC(50) 1.5 &mgr;g/ml) and T. cruzi (IC(50) 11.8 &mgr;g/ml)."
Sener B., Orhan I., Satayavivad J. 2003. Antimalarial activity screening of some alkaloids and the plant extracts from Amaryllidaceae. Phytother. Res., 17: 1220-1223.
Insecticide
Abbassy, M. A., G. O. A. El, et al. 1998. Insecticidal, acaricidal and synergistic effects of Soosan, Pancratium maritimum extracts and constituents. Journal of the Egyptian Society of Parasitology 28(1): 197-205. [abstract]
Pettit, G. R., G. R. I. Pettiti, et al. (1995). Antineoplastic agents, 301. An investigation of the Amaryllidaceae genus Hymenocallis. Journal of Natural Products Lloydia 58(5): 756-759.
Weniger B., Italiano L., Beck J.-P., Bastida J., Bergónon S., Codina C., Lobstein A., Anton R. 1995. Cytotoxic activity of Amaryllidaceae alkaloids. Planta Med., 61: 77-79.
Polt R. 1996. Amaryllidaceae alkaloids with antitumor activity. Org. Synth., 3: 109-148.
Hua, D.H., S. Saha and D.J. Takemoto. 1997. Anticancer activities of 2,5,8,9-substituted 6-oxo-1,2,3,4,5,6-hexahydrophenanthridines on multi-drug-resistant phenotype cells. Anticancer Res. "In Press."
NB : dérivés de la Lycorine.
Tram, Ng. Th. Ng.; E. Zvetkova, E. Nikolova, E. Katzarova, G. K, I. Yanchev, O. Baicheva. 1999. A novel in vitro and in vivo T-lymphocyte activating factor in Crinum latifolium (L.) aqueous extracts. Experimental Pathology and Parasitology. (1999)3:21-26.
[Texte : www.iepp.bas.bg/305EPP1999_21-26.pdf]
Anti-inflamatoire
Çitogğlu G., Tanker M., Gümüs#351;el B. 1998. Antiinflammatory effects of lycorine and haemanthidine. Phytother. Res., 12: 205-206.
Elgorashi E.E., Zschocke S., van Staden J. 2003. The anti-inflammatory and antibacterial activities of Amaryllidaceae alkaloids. South African Journal of Botany, 69(3): 448-449.
Botha E.W., Kahler C.P., Plooy W.J.du, Plooy S.H.du, Mathibe L. 2005. Effect of Boophone disticha on human neutrophils. Journal of Ethnopharmacology, 96(3): 385-388.
Antalgique
Mekin Tanker, Gülçin Çitoglu, Bülent Gümüsel and Bilge Sener: Alkaloids of Sternbergia clusiana and their Analgesic Effects. International Journal of Pharmacognosy. Volume 34 Number 3 July 1996.
[abstract : www.swets.nl/sps/journals/ijp3403.html#anchor917866]
ICLAL ÇAKICI, HEDIYE Y. ULUG, SIBEL INCI, BAHAR TUNÇTAN, NURETTIN ABACIOGLU, ILKER KANZIK & BILGE SENER. 1997. Antinociceptive Effect of some Amaryllidaceae Plants in Mice. J. Pharm. Pharmacol. 49(8): 828 - 830. [Abstract : http://dspace.dial.pipex.com/jpp/j97070.htm]
Anxiolytique
Sandager M., Nielsen N.D., Stafford G.I., Staden J.van, Jäger A.K. 2005. Alkaloids from Boophane disticha with affinity to the serotonin transporter in rat brain. Journal of Ethnopharmacology, 98(3): 367-370.
Divers
Ingkaninan, K.; H. Irth, R. Verpoorte. 2002. Screening of Amaryllidaceae for biological activities: Acetylcholineesterase inhibitors in Narcissus. The genus Narcissus. G.R. Hanks (Editor) Harwood Publishers, London, 369-379.
Weniger, B., Italiano, L., Beck, J.P., Bastida, J., Bergoñón, S., Codina, C., Lobstein, A. y Anton, R.; 1995; Cytotoxic activity of Amaryllidaceae alkaloids; Planta Med., 61: 77-79.
Kushida, N., S. Atsumi, T. Koyano & K. Umezawa. 1997. Induction of flat morphology in K-ras-transformed fibroblasts by lycorine, an alkaloid isolated from the tropical plant Eucharis grandiflora. Druds Exptl. Clin. Res. 23: 151-155.